Monday, December 11, 2023

From Micro organism to Folks: Slavery in Hide


“Small Natural Robots”

We’re in a unusual spot. For a very long time, our tradition has been assuming that nature is our belongings and our slave. An unruly and adverse slave — a slave to be tamed, ruled, and abused — so long as we will escape with it and be ok with ourselves as we dominate.

An element of that mindset is that human beings are seen via probably the most robust other folks in society as their slaves, too. You’ll be heart magnificence and even higher heart magnificence … they don’t care. Of their thoughts, you’re their toy, exist for them. And because it is going, regardless of the masters to do to nature or to the animals, they to do the folk subsequent.

As an example, as an increasing number of other folks moved to towns, we have been advised to undertake the dependancy of essentially chipping, vaccinating, and neutering our pets. It’s all for their very own just right, proper? Neatly, it began with chipping pets however now … I digress.

This tale is concerning the micro organism. Once they discuss programmable micro organism or “micro organism with programmable DNA,” I see it as twin risk, At the one hand, I will’t lend a hand however take into accounts the truth that to our masters, human beings at the flooring aren’t any other than micro organism. Individuals are a useful resource to them — and they don’t seem to be shy about their need to program organic lifestyles, together with human lifestyles. That a lot, we all know.

Secondly, we don’t know anything else concerning the long-term protection of the goods produced with genetically changed insects. And lately, genetically changed microbes are a big and nonetheless rising medium for the economic manufacturing of chemicals, meals, drugs, healing proteins, and so forth. And allegedly, producers don’t even wish to label such merchandise as GMO.

Bioengineered Meals: An Interlude

Bioengineered” is the newest time period for GMO. Here’s a quote from the web page at the U.S. Division of Agriculture site that comprises producer FAQs. I’m the use of their phrases verbatim in order that we will get laws and definitions instantly out in their mouth.

Q: What information are enough to make sure {that a} meals is sourced from a non-bioengineered crop?

Plenty of information could also be enough to make sure a meals is sourced from a non-bioengineered crop. A non-exhaustive checklist comprises: natural certification, information that display a non-BE crop selection used to be used, and information that display a meals originated in a space the place that exact BE meals isn’t produced.

Q: What’s the threshold for bioengineered substance, and the way is it measured?

The edge is designed to acknowledge the realities of the availability chain and recognize that BE and non-BE meals and substances are continuously grown, harvested, transported, and processed in shut proximity to each other. As a result of this fact, even if a non-BE factor is used, there could also be a hint quantity of a BE substance that continues to be on shared apparatus.

The edge exempts meals by which no factor deliberately comprises a bioengineered substance and lets in for the inadvertent or technically unavoidable presence of a BE substance, of as much as 5 %, in every factor.

Q: I’m a regulated entity that can qualify for the very small meals producers exemption. How do I calculate my overall income?

The Usual at 7 CFR 66.5(b) exempts very small meals producers from the BE disclosure necessities. At 7 CFR 66.1, very small meals producers are outlined as any meals producer with annual receipts of not up to $2,500,000 USD.

This quantity comprises all meals and non-food receipts. Meals producer is outlined as an entity that manufactures, processes, or packs human meals and labels the meals or meals product for retail sale.

Q. What’s a validated refining procedure?

A validated refining procedure is one who has been demonstrated to make changed genetic subject material undetectable when adopted. Validation is showed via trying out and thru repairs of processing information.

AMS has printed a steering on validation and to choose a take a look at way. Each the steering paperwork and related FAQs can also be discovered below detectability trying out.

Q. As soon as I’ve validated {that a} refining procedure makes changed genetic subject material undetectable, do I wish to proceed to check that procedure?

No, as soon as a procedure has been validated via trying out and a regulated entity maintains information appearing the validated procedure is adopted, the method does no longer wish to be examined once more except vital adjustments are made to that refining procedure.

And some other quote:

Q. If a uncooked subject material has processing aids that aren’t categorised within the factor checklist on our completed product, would that be matter to disclosure below the Usual? As an example, we use a nutrition D that has a corn oil provider. We label the nutrition D on our completed product, however no longer the corn oil. If we all know the nutrition D isn’t a bioengineered meals, does the completed product want a BE disclosure as a result of the corn oil provider?

The definition of bioengineered meals, at 7 CFR 66.1, excludes incidental components which are found in meals at a mere stage and that wouldn’t have any technical or practical impact within the meals, as described in 21 CFR 101.100(a)(3). Incidental components, when used in response to this definition, aren’t required to be incorporated at the factor checklist.

If the corn oil you’re the use of as a processing assist is thought of as an incidental additive as outlined in 21 CFR 101.100(a)(3), then it does no longer require a bioengineered meals disclosure.

Are you inspired with those labeling requirements? It’s not that i am.

Precision Fermentation

Precision fermentation is a method by which microorganisms are genetically reprogrammed to supply explicit, custom designed molecules that may function new meals substances, commercial chemical substances, healing proteins, vaccines, and so forth. Even though the long-term results of such merchandise are unknown, from the trade point of view, precision fermentation is thought of as really useful as it’s doubtlessly inexpensive and extra scalable than generating chemical substances at once from vegetation, and so forth.

In step with Forbes, it’s a “new meals generation this is abruptly getting into the mainstream. Merchandise corresponding to milk protein, animal fat, collagen, honey, lobster, egg whites and extra are receiving loads of thousands and thousands of investor greenbacks … Those merchandise are being advertised to a tender client base that wishes sustainable, climate-friendly meals that greenback the machine and promise a greater the following day.” Hmmm, however is it so?

“Precision fermentation generation is a type of artificial biology … that most often calls for using genetically engineered microorganisms, which might be cultivated in brewery-style fermentation tanks. The little critters, normally yeast, algae or micro organism, are programmed via a variety of in-vitro nucleic acid ways corresponding to CRISPR, gene enhancing or cloning.

They produce or excrete a selected sellable subject material, normally suitable for eating fat or proteins which are biologically very similar to animal merchandise. Those finish merchandise can also be additional processed into substances or completed CPG pieces.”

“The … new Nationwide Bioengineered Meals Disclosure Usual would no longer require those meals to be categorised as GMO as a result of they don’t comprise the genetically engineered organisms, they’re simply produced via them. Such merchandise would subsequently no longer qualify for Non GMO Venture Verification. As a result of some could also be thought to be novel meals, it’s not transparent how they are going to be categorised or regulated in Europe.

And because they’re animal-free, they could also be thought to be vegan, however will nonetheless wish to have the similar allergen labeling as their animal-based opposite numbers.”

What concerning the mobile tradition medium? Is it in reality as impartial and insignificant as we’re resulted in consider?? Even Forbes has query. “Is the nutrient tub derived from corn or soy, most often genetically changed to resist excessive dosages of herbicides? Are there provide chains in position to offer such nutrient media at scale? […] How a lot waste subject material is produced via such microorganisms relative to sellable product?

This comprises metabolic wastes, in addition to the leftover steep as soon as the spent microbes and consumable subject material had been filtered out. How will such wastes be disposed of and who’s in the end answerable for it?”

Oh forestall asking foolish questions, says the trade. In step with Meals Navigator, in its 2020 record on precision fermentation in dairy, RethinkX predicted that the generation would make protein manufacturing “5 occasions inexpensive via 2030 and 10 occasions inexpensive via 2035 than present animal proteins.”

The “promotional brochure” for the goods made with precision fermentation would have you ever consider that they’re herbal and secure. Precision fermentation, alternatively, is “not anything like its herbal counterpart … It makes use of genetically engineered microorganisms, corresponding to yeast and micro organism, which are fermented in brewery-style tanks below high-tech, pharmaceutical grade sterile prerequisites.

It is because those cultures are extremely prone to contamination which might damage all the batch … The long-term results are utterly unknown … However it is all serving the underlying time table, which is overall regulate and international domination … Those faux, ultraprocessed meals give the globalists unparalleled chronic and regulate over human well being, and they are the use of stealthy advertising ways.”

“Herbal Merchandise”

“Herbal merchandise” may be a proper time period to explain a selected form of metabolite, the secondary metabolite. In step with this Harvard College article, some organisms, corresponding to vegetation, fungi and micro organism, are in a position to create a category of molecules referred to as secondary metabolites, or herbal merchandise.

Researchers consider that they play no direct function within the organism’s customary expansion or copy as eliminating those molecules from the organism does no longer lead to quick demise. Alternatively, the ones organisms depend on herbal merchandise designed for explicit duties, corresponding to coverage in opposition to different organisms or interplay with their very own species.

“As a result of those molecules are made to impact different organisms in quite a lot of techniques, they are able to be very helpful as therapeutics. As an example, they are able to be used to kill destructive micro organism infecting people, and even have an impact at once on human cells for quite a lot of healing functions. In reality, maximum of our drugs are in fact derived from or impressed via herbal merchandise.”

“One essential use of herbal merchandise is antibiotics. Ever for the reason that serendipitous discovery of penicillin in 1928, which used to be a herbal product from fungi that might kill micro organism … Along with antibiotics, many bacterial herbal merchandise produce other healing makes use of.

As an example, rapamycin, sometimes called sirolimus, is made via the micro organism Streptomyces hygroscopicus, and is used clinically as an immunosuppressant, particularly right through a kidney transplant. Bleomycin, a herbal product discovered from Streptomyces verticillus, is a chemotherapy drug used within the remedy for a variety of cancers.”

Commercial Microbiology

Microorganisms play a vital function in commercial manufacturing, and new processes involving microbes are being researched as we talk.

As an example, micro organism can doubtlessly “heal” concrete. Researchers on the College of Tub are investigating how some species of Bacillus micro organism might be used to make concrete that may “heal” itself.

As a skeptical peasant with out a revel in in development, I’m fascinated with “therapeutic” concrete however I for sure hope that they take a look at this subject material completely to make certain that the spores they search to combine into the concrete don’t “leach” and make the whole thing round us some roughly a GMO spore fest.

Medical Wisdom Is Restricted

Genetically changed microbes sound nice for the base line — however do the scientists know in earnest how issues paintings, and what ends up in what? Are they certain? If we’re to consider this paper, they don’t seem to be.

“In spite of mounting proof linking host-associated micro organism to customary building and illness in animal fashions and correlative proof in people, the mechanisms during which explicit bacterial purposes have an effect on mammalian or microbiome body structure (i.e., effector purposes) stay in large part undefined [emphasis mine].

The central dogma of molecular biology, historically defined because the switch of knowledge from DNA to RNA to protein, stops wanting without equal finish level of a lot of the guidelines float in a organic machine. In a vital fraction of cell processes, the top level of knowledge float isn’t a protein however is, as an alternative, a small molecule.

That is very true for micro organism which depend closely on low-molecular-weight compounds (i.e., small molecules or herbal merchandise) to engage with their environment. The systematic characterization of small molecules produced via human-associated micro organism will indubitably be key to interpreting the mechanistic main points of the function the human microbiome performs in our well being and illness.”

Bacterial Biosensors

In step with a paper titled “Bacterial biosensors: The way forward for analyte detection,” micro organism include numerous sensors — and, in keeping with Caroline Ajo-Franklin, Ph.D., a professor of biosciences at Rice College whose artificial biology lab develops microbial biosensors, “those sensors do not simply sense, they [also] inform the micro organism to do one thing.”

The researchers need to “leverage the ones herbal responses to have the micro organism let us know, as people, what they are seeing [and] what they are feeling.”

The overall theory of a whole-cell microbial biosensor is to program a mobile (most often via genetic engineering) to acknowledge and generate a measurable sign in accordance with a particular molecule. When producing biosensors, scientists “co-opt those responses [with a transducer] in order that as an alternative of getting cells that simply make [products like] efflux pumps, [researchers] engineer them to create a reaction [the scientists] can learn.”

“Relying at the biosensor and its meant use, this reaction can also be electrochemical or contain expression of fluorescent or luminescent reporter proteins. Complete-cell biosensors are continuously engineered to paintings simplest when their goal molecule is provide. This skill to fine-tune specificity and sensitivity has made bacterial biosensors promising analytical gear.”

Complete-cell biosensors can “supply perception on nutrient ranges and natural compounds in soils, which is able to tell strategies for managing crop expansion. They are able to additionally sign the presence and ranges of doubtless problematic compounds.”

“Along with vitamins and poisonous compounds, bacterial biosensors can also be designed to reply to … different micro organism. Microbes secrete all kinds of metabolites, a lot of which might function goal analytes. As an example, microbial biosensors that stumble on quorum sensing molecules secreted via bacterial pathogens can sign the presence of disease-causing microbes in water, or in human samples to lend a hand diagnose infections.”

“Bacterial biosensors would possibly supply helpful intel into the well being of human sufferers. A fresh find out about described a biosensor comprised of the environmental bacterium, Acinetobacter baylyi, that may stumble on DNA from most cancers cells in vitro and in a mouse fashion. This find out about supplies a foundation for the applying of microbial biosensors in most cancers detection and analysis.

Scientists have additionally created ingestible biosensors that may stumble on bleeding or inflammatory biomarkers within the intestine to watch intestinal well being; the alerts from those inside microbial gadgets can also be transmitted to exterior gadgets, like cell phones, thus illustrating how biosensors can also be paired with present virtual applied sciences to facilitate knowledge assortment and research.”

My two cents? At the one hand, it’s superb with the intention to stumble on pollution round us (assuming it really works). It might be superb however … however the issue is that as same old, the scientists don’t have any clue about what’ll occur in the long run. Will those so referred to as “small natural robots” lend a hand with something and damage ten different issues? And the way can we even blank up? Scientists don’t appear to care. Traders giggle on the very idea. And who can be caught with the invoice? Our our bodies. Us.

Graphene Oxide within the Mind: Yay

Talking of getting no clue, this 2023 paper titled, “Graphene Oxide Attenuates Toxicity of Amyloid-β Aggregates in Yeast via Selling Disassembly and Boosting Mobile Pressure Reaction,” talks about the use of graphene oxide to lend a hand with Alzheimer’s illness.

What an excellent thought! The way is in accordance with the power of GO nanoflakes to counter the aggregation of misfolded amyloid-β (Aβ) peptides within the mind. However what if the ones misfolded proteins are the mind’s reaction to an infection?

In the end, the “infectious” principle of Alzheimer’s illness has been recognized for some years, and an infection and ensuing irritation might be outstanding components in creating AD. Then need? Are we simply going to wash the mind in GO nanoflakes till the individual drops useless? To not point out GO toxicity, conductivity, and the Web of Issues. Jeez.

“Alzheimer’s illness (AD) is probably the most prevalent neurodegenerative illness, with the aggregation of misfolded amyloid-β (Aβ) peptides within the mind being one in all its histopathological hallmarks. Just lately, graphene oxide (GO) nanoflakes have attracted vital consideration in biomedical spaces because of their capability of suppressing Aβ aggregation in vitro.

The mechanism of this really useful impact has no longer been totally understood in vivo. Herein, the affect of GO on intracellular Aβ42 aggregates and cytotoxicity is investigated the use of yeast Saccharomyces cerevisiae because the fashion organism. This find out about unearths that GO nanoflakes can successfully penetrate yeast cells and cut back Aβ42 toxicity.

Aggregate of proteomics knowledge and follow-up experiments display that GO remedy alters cell metabolism to will increase cell resistance to misfolded protein tension and oxidative tension, and decreases quantities of intracellular Aβ42 oligomers. Moreover, GO remedy additionally reduces HTT103QP toxicity within the Huntington’s illness (HD) yeast fashion.

The findings be offering insights for rationally designing GO nanoflakes-based remedies for attenuating cytotoxicity of Aβ42, and doubtlessly of alternative misfolded proteins serious about neurodegenerative pathology.”

Want for Keep watch over … and Us

It seems like numerous this artificial insanity is pushed via the need to regulate. The need to regulate performs the most important function in our tradition and in our clinical paradigms. All in all, we live below the guideline of loopy maniacs who search absolute regulate! It’s an excessively distorted, neurotic, joyless rule.

The loopy maniacs — the dominators, the power-seeking mental sort — had been at the back of each and every giant atrocity, each and every no longer so nice reset for hundreds of years on finish, each and every main abuse. And they don’t seem to be letting cross.

Sure, I consider that what’s using the no longer so nice reset is need for regulate. That need has been using our civilization for somewhat some time. It is extremely logical that the individuals who need to have regulate search to interchange the wildlife with a man-made international. In a man-made international, they are able to impose their laws. An artificial international, they are able to regulate — or a minimum of check out. So what will we do?

I consider that what we do is keep vigilant, teach ourselves, stay issues in point of view, and demand at the legitimacy of our love of lifestyles. The aspiring masters need us to be afraid and unhappy. They would like us to carry our head down and to be slaves. However we aren’t slaves! And if we do completely the whole thing from the location of affection — sturdy, assured, non-push-over love — we will be able to end up no longer simply with our phrases however with our movements that we aren’t slaves. As a result of slaves, we aren’t.

Concerning the Writer

To search out extra of Tessa Lena’s paintings, be sure that to take a look at her bio, Tessa Fights Robots.


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