Sunday, September 24, 2023

The load loss drug Wegovy might do greater than lend a hand folks drop pounds : NPR


New trial effects display the weight-loss drugs Wegovy too can lower center assault and stroke dangers, in line with the drug’s maker.


The maker of Wegovy is claiming the burden loss drug too can lower the danger of center assaults and strokes. NPR’s Allison Aubrey studies.

ALLISON AUBREY, BYLINE: It is no secret that Wegovy, like its counterpart Ozempic, is in top call for. Those medication are very efficient at serving to folks regulate urge for food and arrange weight. Now, Novo Nordisk, the maker of Wegovy, has effects from a five-year find out about that display folks with weight problems or who’re obese that take the drug have a few 20% decreased chance of getting a big cardiac tournament, equivalent to a center assault or stroke. Here is doctor Steven Nissen, a heart specialist on the Cleveland Sanatorium who was once now not concerned within the find out about.

STEVEN NISSEN: It is a very promising consequence, however how promising depends on different issues.

AUBREY: The result of the find out about, which incorporated about 17,000 adults, have now not but been revealed in a peer-reviewed magazine. And Dr. Nissen says key main points equivalent to doable dangers aren’t incorporated within the corporate’s press free up. He says the aid in center assaults and strokes turns out very vital.

NISSEN: We now know that there’s a get advantages, and that is the reason nice, however we do not know what the dangers are. And it is all the time about get advantages as opposed to chance with any drug, and we want to see all of that.

AUBREY: Dr. Nissen is learning a equivalent drug, Mounjaro, in an ongoing medical trial. Dr. Pamela Brandt of Inova Well being Gadget treats sufferers with weight problems and says Wegovy does have some not unusual uncomfortable side effects.

PAMELA BRANDT: Other folks really feel complete a lot more briefly however that may additionally result in nausea or an build up in acid reflux disorder or feeling simply uncomfortably complete.

AUBREY: Uncommon uncomfortable side effects come with the danger of pancreatitis and, in rodent research, a chance of thyroid tumors. So docs display screen sufferers for a circle of relatives historical past of a selected more or less thyroid most cancers. The findings of the brand new find out about come amid a debate about whether or not Medicare will have to pay for the blockbuster weight reduction medication. And Dr. Brandt says the brand new analysis presentations that weight reduction for those sufferers isn’t about vainness or appearances. It is about combating illness.

BRANDT: The entire function of treating folks to lend a hand them succeed in weight reduction is to cause them to fitter. So seeing that they in reality have a lowered chance of cardiovascular occasions like center assaults and strokes, that is what’s truly essential.

AUBREY: Brandt says she seems to be ahead to seeing the entire main points and what can be a landmark find out about.

Allison Aubrey, NPR Information.


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